Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099714 | 0.91 | TP53 (0.35) | MAPTTP53ALDH1A1 | |
| SCHEMBL9100834 | 0.87 | TP53 (0.34) | MAPTTP53 | |
| SCHEMBL9098811 | 0.84 | MAPT (0.32) | MAPTTP53ALDH1A1 | |
| SCHEMBL9100443 | 0.81 | TP53 (0.30) | MAPTTP53 | |
| SCHEMBL9097611 | 0.75 | MAPT (0.36) | MAPT | |
| SCHEMBL19798776 | 0.70 | MAPT (0.34) | MAPTALDH1A1RAB9A | |
| SCHEMBL9101169 | 0.70 | NR1H2 (0.38) | MAPTTP53ALDH1A1RAB9A | |
| SCHEMBL9101666 | 0.68 | MAPT (0.34) | MAPT | |
| SCHEMBL9100099 | 0.63 | RAF1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL19798775 | 0.62 | RAPGEF4 (0.38) | MAPTTP53ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415303-B1 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1995-12-13 | — | — | EP | claimed |