Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097611 | 0.85 | MAPT (0.36) | POLBMAPT | |
| SCHEMBL9101666 | 0.85 | MAPT (0.34) | POLBMAPT | |
| SCHEMBL9103407 | 0.80 | PIK3CD (0.38) | POLBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9098811 | 0.72 | MAPT (0.32) | POLBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9100124 | 0.65 | NR1H2 (0.40) | POLBMAPTMEN1KMT2A | |
| SCHEMBL19138410 | 0.62 | ALPL (0.47) | RAF1 | |
| SCHEMBL9101244 | 0.62 | CASP1 (0.45) | MEN1ALDH1A1KMT2A | |
| SCHEMBL25327651 | 0.61 | ALDH1A1 (0.63) | POLBMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL19138494 | 0.61 | ALPL (0.48) | RAF1 | |
| SCHEMBL19138423 | 0.61 | ALPL (0.48) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550122-A | INHIBIT REVERSE TRANSCRIPTASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | claimed |
| EP-0415303-B1 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1995-12-13 | — | — | EP | claimed |
| EP-0451760-B1 | Nitrato alkanoic acid derivatives and method for their production | SANOL ARZNEI SCHWARZ GMBH (DE) | 1995-09-13 | — | — | EP | claimed |
| EP-0415303-A2 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-03-06 | — | — | EP | claimed |
| US-5550122-A | INHIBIT REVERSE TRANSCRIPTASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0415303-B1 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0415303-A2 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-03-06 | — | — | EP | disclosed |