Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.55 |
| ▸ | DRD2 | P14416 | 9/20 | 0.55 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222650 | 0.72 | DRD2 (0.53) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL8027345 | 0.71 | DRD4 (1.00) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL9221790 | 0.70 | CCNA2 (0.47) | DRD4DRD2 | |
| SCHEMBL9219954 | 0.70 | DRD4 (0.55) | DRD4DRD2CCNCCDK8CDK19 | |
| Hydrochloric Acid SCHEMBL8022012 | 0.70 | DRD4 (0.97) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL21614788 | 0.66 | DRD2 (0.49) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL8022043 | 0.66 | DRD4 (1.00) | DRD4DRD2CCNCCDK8CDK19 | |
| Hydrochloric Acid SCHEMBL8011148 | 0.65 | DRD4 (0.97) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL7246869 | 0.64 | DRD4 (0.68) | DRD4DRD2CCNCCDK8CDK19 | |
| SCHEMBL13085158 | 0.64 | DRD2 (0.50) | DRD4DRD2CCNCCDK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276833-B1 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMA (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0276833-A2 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4734430-A | Dipyrazoles and their use as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |