Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212691 | 1.00 | RAB9A (0.43) | RAB9ANPC1GAAALDH1A1HSD17B10 | |
| SCHEMBL10265478 | 0.78 | RAB9A (0.48) | RAB9ANPC1GAAALDH1A1HSD17B10 | |
| SCHEMBL4572089 | 0.77 | RAB9A (0.47) | RAB9ANPC1GAAALDH1A1HSD17B10 | |
| SCHEMBL5642898 | 0.73 | RAB9A (0.50) | RAB9ANPC1GAAALDH1A1HSD17B10 | |
| SCHEMBL9211419 | 0.73 | NOS1 (0.53) | RAB9ANPC1KMT2ASMN1; SMN2CES2 | |
| SCHEMBL3455076 | 0.71 | POLB (0.52) | RAB9ANPC1GAAALDH1A1KMT2A | |
| SCHEMBL3455077 | 0.71 | POLB (0.52) | RAB9ANPC1GAAALDH1A1KMT2A | |
| SCHEMBL27616301 | 0.70 | RAB9A (0.40) | RAB9ANPC1GAAALDH1A1HSD17B10 | |
| SCHEMBL9211615 | 0.69 | MAPT (0.40) | RAB9ANPC1GAAALDH1A1HDAC1 | |
| SCHEMBL9211607 | 0.69 | MAPT (0.40) | RAB9ANPC1GAAALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | disclosed |