Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455076 | 1.00 | POLB (0.52) | POLBTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9217149 | 0.81 | CA2 (0.41) | POLBKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9532199 | 0.81 | RAB9A (0.38) | TSHRKMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9532178 | 0.81 | SMN1; SMN2 (0.37) | KMT2AALDH1A1NPC1MAPTL3MBTL1 | |
| SCHEMBL9532175 | 0.81 | SMN1; SMN2 (0.37) | KMT2AALDH1A1NPC1MAPTL3MBTL1 | |
| SCHEMBL30827437 | 0.81 | GSK3B (0.40) | KMT2AALDH1A1RAB9ANPC1PRSS1 | |
| SCHEMBL9217151 | 0.81 | CA2 (0.41) | POLBKMT2AALDH1A1MAPTGAA | |
| SCHEMBL15288624 | 0.80 | NPC1 (0.53) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6444890 | 0.79 | POLB (0.47) | POLBTSHRIDO1KMT2AALDH1A1 | |
| SCHEMBL6444893 | 0.79 | POLB (0.47) | POLBTSHRIDO1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920017-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| EP-2384322-B1 | PYRIMIDINE DERIVATIVES AND USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8445408-B2 | Pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AG (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-2206703-A1 | Pyrimidine derivatives and use thereof for combating undesired plant growth | Bayer CropScience AG (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-20100167935-A1 | Pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
| US-7396830-B2 | Piperazine amidines as antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-08 | — | — | US | disclosed |
| EP-1911753-A1 | SPIRO-CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20070078141-A1 | Piperazine amidines as antiviral agents | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078141-A1 | Piperazine amidines as antiviral agents | IDO1, IDO2, EIF2AK2 | POLB 1296/4885TSHR 4270/4885PDE4A 95/4885 |
| US-20100167935-A1 | Pyrimidine derivatives and their use for controlling undesired plant growth | TYMS, TYMP, UMPS | POLB 63/4885TSHR 3885/4885PDE4A 1307/4885 |
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | POLB 4607/4885TSHR 3119/4885PDE4A 551/4885 |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | ACACA, CPT1B, PC | POLB 3928/4885TSHR 2537/4885PDE4A 2592/4885 |
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | POLB 1544/4885TSHR 4278/4885PDE4A 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.