SCHEMBL921271

SCHEMBL921271

COc1cccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.57
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
POLB P06746 2/20 0.57
KDM4E B2RXH2 1/20 0.55
USP2 O75604 1/20 0.55
MAPK8 P45983 2/20 0.53
EGLN1 Q9GZT9 2/20 0.53
MMP13 P45452 1/20 0.50
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50
TUBB3 Q13509 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920983 0.93 HPGD (0.67) HPGDLMNAKMT2AALDH1A1MEN1
SCHEMBL921037 0.92 HPGD (0.66) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL920077 0.92 HPGD (0.62) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL920160 0.91 HPGD (0.56) HPGDLMNASMN1; SMN2KMT2AMAPK8
SCHEMBL920714 0.89 MAPK8 (0.53) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL921981 0.89 HPGD (0.70) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL921939 0.89 MAPK8 (0.50) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL921082 0.89 MAPK8 (0.50) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL919798 0.88 MAPK8 (0.55) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL923068 0.88 HPGD (0.72) HPGDLMNAKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.