Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213079 | 0.93 | FFAR1 (0.37) | FFAR1KDM4EPPARAPPARGSMN1; SMN2 | |
| SCHEMBL9215417 | 0.84 | MEN1 (0.36) | FFAR1KMT2AS1PR1 | |
| SCHEMBL9215653 | 0.80 | FFAR1 (0.47) | FFAR1SMN1; SMN2KMT2A | |
| SCHEMBL9219849 | 0.80 | MTNR1A (0.35) | MAPT | |
| SCHEMBL9209788 | 0.80 | NPC1 (0.47) | KDM4ESMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL9208968 | 0.79 | PPARG (0.41) | PPARAPPARGKMT2AS1PR1 | |
| SCHEMBL9211087 | 0.78 | NPC1 (0.35) | FFAR1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9275150 | 0.77 | MEN1 (0.37) | FFAR1KMT2A | |
| SCHEMBL9215312 | 0.76 | MAPT (0.34) | KMT2AMAPT | |
| SCHEMBL9212152 | 0.76 | PPARG (0.34) | KDM4EPPARAPPARGKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | claimed |
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | disclosed |