Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208876 | 0.99 | HRH3 (0.36) | HRH3HTR7ALDH1A1KDM4ELMNA | |
| SCHEMBL9207422 | 0.93 | HRH3 (0.40) | HRH3ALDH1A1KDM4ELMNALTA4H | |
| SCHEMBL9208037 | 0.91 | HRH3 (0.37) | HRH3ALDH1A1KDM4ELMNALTA4H | |
| Hydrochloric Acid SCHEMBL9740263 | 0.90 | ALOX15 (0.42) | ALDH1A1KDM4EHTR1AKCNH2GAA | |
| Hydrochloric Acid SCHEMBL9739549 | 0.90 | ALOX15 (0.42) | ALDH1A1KDM4EHTR1AKCNH2GAA | |
| SCHEMBL9206630 | 0.90 | ALOX15 (0.43) | ALDH1A1KDM4EHTR1AKCNH2GAA | |
| SCHEMBL9208761 | 0.90 | NPC1 (0.35) | HRH3HTR7ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9740340 | 0.89 | ALOX15 (0.43) | ALDH1A1KDM4EHTR1AKCNH2GAA | |
| SCHEMBL9206564 | 0.89 | NPC1 (0.36) | HRH3HTR7ALDH1A1KDM4ELMNA | |
| SCHEMBL9216033 | 0.88 | ATM (0.39) | HRH3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |