Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8971928 | 0.99 | CYP19A1 (0.38) | CYP19A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8954174 | 0.90 | GPBAR1 (0.38) | CYP19A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9214006 | 0.87 | GPBAR1 (0.40) | RAB9AMEN1KMT2APOLBBLM | |
| SCHEMBL9531170 | 0.77 | GPBAR1 (0.41) | RAB9AMEN1KMT2AGPBAR1GAA | |
| SCHEMBL7382228 | 0.71 | ACE2 (0.43) | RAB9AMEN1KMT2APOLBGPBAR1 | |
| Hydrochloric Acid SCHEMBL6926762 | 0.69 | SMN1; SMN2 (0.47) | CYP19A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL1951714 | 0.69 | CYP11B1 (0.69) | RAB9AMEN1KMT2APOLBBLM | |
| SCHEMBL6929338 | 0.69 | CYP11B1 (0.51) | CYP19A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL10795646 | 0.67 | SMN1; SMN2 (0.44) | CYP19A1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9453967 | 0.67 | LMNA (0.37) | MEN1KMT2APOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |