Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8130088 | 0.70 | BRS3 (0.46) | LMNAKDM4EMAPTPOLBBRS3 | |
| SCHEMBL8114878 | 0.70 | BRS3 (0.51) | LMNAKDM4EMAPTPOLBBRS3 | |
| SCHEMBL9213182 | 0.67 | CYP19A1 (0.39) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9491397 | 0.66 | LMNA (0.46) | LMNAKDM4EMAPTPOLBBRS3 | |
| Hydrochloric Acid SCHEMBL8971928 | 0.66 | CYP19A1 (0.38) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7055679 | 0.65 | PIN1 (0.38) | LMNAPOLBBRS3SMN1; SMN2PKM | |
| SCHEMBL7993249 | 0.61 | LMNA (0.52) | LMNAKDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4018722 | 0.60 | TAAR1 (0.67) | LMNAKDM4EMAPTKMT2ATAAR1 | |
| SCHEMBL16020970 | 0.60 | MPO (0.40) | LMNAKDM4EMAPTSMN1; SMN2TAAR1 | |
| SCHEMBL29519238 | 0.59 | IDO1 (0.62) | LMNAPKMDAOTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248689-A | Hypotensive agents, congestive heart failure, renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |