SCHEMBL921345

SCHEMBL921345

CSc1ccccc1Oc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.56
LMNA P02545 3/20 0.53
GAA P10253 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPK8 P45983 1/20 0.51
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.45
MAPK14 Q16539 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922627 0.90 HPGD (0.58) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL919733 0.89 KMT2A (0.50) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL920963 0.87 HPGD (0.50) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL921143 0.86 CARM1 (0.56) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL919966 0.86 MAPK14 (0.61) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL921012 0.86 HPGD (0.53) HPGDLMNAKMT2AMAPK8ALDH1A1
SCHEMBL921204 0.86 HPGD (0.54) HPGDLMNAGAAKMT2AALDH1A1
SCHEMBL920515 0.85 HPGD (0.57) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL920905 0.85 MAPK8 (0.53) HPGDLMNAGAAKMT2AMAPK8
SCHEMBL921176 0.85 HPGD (0.54) HPGDLMNAKMT2AMAPK8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885GAA 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.