SCHEMBL920963

SCHEMBL920963

CSc1ccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c(C)c1C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.50
MAPK8 P45983 1/20 0.46
LMNA P02545 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 1/20 0.44
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.43
EGLN1 Q9GZT9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921345 0.87 HPGD (0.56) HPGDMAPK8LMNASMN1; SMN2GAA
SCHEMBL920553 0.84 LMNA (0.54) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL921012 0.84 HPGD (0.53) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL919887 0.83 HPGD (0.48) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL920672 0.83 HPGD (0.48) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL921176 0.83 HPGD (0.54) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL919966 0.82 MAPK14 (0.61) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL922484 0.81 HPGD (0.62) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL920225 0.81 LIPG (0.52) HPGDMAPK8LMNASMN1; SMN2POLB
SCHEMBL921191 0.81 MAPK8 (0.50) HPGDMAPK8LMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885MAPK8 2313/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.