Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 2/20 | 0.30 |
| ▸ | F3 | P13726 | 2/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459528 | 1.00 | ALDH1A1 (0.34) | ALDH1A1ALOX15CXCR3KDM4ETDP1 | |
| SCHEMBL9210832 | 0.95 | TSHR (0.32) | ALDH1A1ALOX15KDM4ETDP1MAPT | |
| SCHEMBL60609 | 0.93 | ALDH1A1 (0.36) | ALDH1A1ALOX15CXCR3KDM4ETDP1 | |
| SCHEMBL7980460 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ALOX15CXCR3PKMTAAR1 | |
| SCHEMBL60610 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EPKMLMNA | |
| SCHEMBL61669 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EPKMLMNA | |
| SCHEMBL7459531 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EPKMLMNA | |
| SCHEMBL6839659 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EPKMLMNA | |
| SCHEMBL28861193 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EPKMLMNA | |
| SCHEMBL7991231 | 0.77 | CXCR3 (0.40) | ALDH1A1ALOX15CXCR3PKMTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |