Sugi Predict

Sugi Predict / Compounds / SCHEMBL60609

SCHEMBL60609

SCHEMBL60609

CCCC[CH]CC1=CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.36
▸ ALOX15 P16050 2/20 0.36
▸ CXCR3 P49682 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ TAAR1 Q96RJ0 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ USP2 O75604 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9213484 0.93 ALDH1A1 (0.34) ALDH1A1ALOX15CXCR3KDM4EMAPT
SCHEMBL7459528 0.93 ALDH1A1 (0.34) ALDH1A1ALOX15CXCR3KDM4EMAPT
SCHEMBL9210832 0.88 TSHR (0.32) ALDH1A1ALOX15KDM4EMAPTTDP1
SCHEMBL7980460 0.81 ALDH1A1 (0.40) ALDH1A1ALOX15CXCR3PKMTAAR1
SCHEMBL7991231 0.79 CXCR3 (0.40) ALDH1A1ALOX15CXCR3PKMTAAR1
SCHEMBL7998167 0.79 CXCR3 (0.40) ALDH1A1ALOX15CXCR3PKMTAAR1
SCHEMBL8126669 0.79 CXCR3 (0.40) ALDH1A1ALOX15CXCR3PKMTAAR1
SCHEMBL31683850 0.77 ALDH1A1 (0.41) ALDH1A1ALOX15KDM4EMAPTATM
SCHEMBL7994428 0.75 — —
SCHEMBL196177 0.75 ALDH1A1 (0.49) ALDH1A1ALOX15PKMTAAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218633-A1 METHODS OF TREATING ORAL MUCOSITIS GALERA LABS, LLC 2023-07-13 — — US disclosed
US-11612608-B2 Methods of treating oral mucositis GALERA LABS, LLC (US) 2023-03-28 — — US disclosed
US-11186560-B2 Arthropod repellent chemicals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-11-30 — — US disclosed
US-20200215077-A1 METHODS OF TREATING ORAL MUCOSITIS BIOSSIL INC. (CA) 2020-07-09 — — US disclosed
US-10610533-B2 Methods of treating oral mucositis GALERA LABS, LLC (US) 2020-04-07 — — US disclosed
EP-3527079-A1 METHODS OF TREATING ORAL MUCOSITIS Galera Labs, LLC (US) 2019-08-21 — — EP disclosed
US-20190194158-A1 ARTHROPOD REPELLENT CHEMICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-06-27 — — US disclosed
EP-2056675-B1 METHODS OF TREATING ORAL MUCOSITIS GALERA LABS LLC (US) 2019-01-09 — — EP disclosed
US-20180333421-A1 METHODS OF TREATING ORAL MUCOSITIS BIOSSIL INC. (CA) 2018-11-22 — — US disclosed
EP-3287464-A1 ONE POT SYNTHESIS OF TETRAZOLE DERIVATIVES OF SIROLIMUS Abbott Laboratories (US) 2018-02-28 — — EP disclosed
WO-1996039396-A1 MANGANESE OR IRON COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1996-12-12 — — WO disclosed
WO-1995028968-A1 DIAGNOSTIC IMAGE ANALYSIS WITH METAL COMPLEXES MONSANTO COMPANY (US) 1995-11-02 — — WO disclosed
EP-0679155-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE. MONSANTO CO (US) 1995-11-02 — — EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 — — EP disclosed
WO-1994015925-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1994-07-21 — — WO disclosed
EP-0598753-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1994-06-01 — — EP disclosed
WO-1993002090-A1 MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE MONSANTO COMPANY (US) 1993-02-04 — — WO disclosed
EP-0524161-A1 Manganese complexes of nitrogen containing macrocyclic ligands effective as catalysts for dismutating superoxide MONSANTO COMPANY (US) 1993-01-20 — — EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 — — US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180333421-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885ALOX15 540/4885CXCR3 2325/4885
US-20190194158-A1 ARTHROPOD REPELLENT CHEMICALS DDT, TRPA1, DHODH ALDH1A1 1333/4885ALOX15 1244/4885CXCR3 88/4885
US-20200215077-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885ALOX15 540/4885CXCR3 2325/4885
US-11186560-B2 Arthropod repellent chemicals DDT, TRPA1, DHODH ALDH1A1 1333/4885ALOX15 1244/4885CXCR3 88/4885
US-20230218633-A1 METHODS OF TREATING ORAL MUCOSITIS LPO, SOD3, MPO ALDH1A1 664/4885ALOX15 540/4885CXCR3 2325/4885
US-10610533-B2 Methods of treating oral mucositis LPO, SOD3, MPO ALDH1A1 664/4885ALOX15 540/4885CXCR3 2325/4885
US-11612608-B2 Methods of treating oral mucositis LPO, SOD3, MPO ALDH1A1 664/4885ALOX15 540/4885CXCR3 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.