Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | RRM1 | P23921 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222769 | 1.00 | MTNR1A (0.43) | MTNR1ARRM1L3MBTL1NR4A2MAPT | |
| SCHEMBL8948874 | 0.89 | MTNR1A (0.43) | MTNR1ARRM1L3MBTL1NR4A2MAPT | |
| SCHEMBL8948885 | 0.89 | MTNR1A (0.43) | MTNR1ARRM1L3MBTL1NR4A2MAPT | |
| SCHEMBL8948898 | 0.89 | MTNR1A (0.43) | MTNR1ARRM1L3MBTL1NR4A2MAPT | |
| SCHEMBL9218125 | 0.85 | MTNR1A (0.44) | MTNR1ANR4A2MAPTMEN1KMT2A | |
| SCHEMBL9214778 | 0.82 | NR4A2 (0.44) | MTNR1ANR4A2PLAUMTNR1BPLK1 | |
| SCHEMBL1668640 | 0.80 | NR4A2 (0.54) | MTNR1AL3MBTL1NR4A2MAPTMEN1 | |
| SCHEMBL9213563 | 0.77 | MRGPRX4 (0.42) | RXFP1RAB9ANPC1 | |
| SCHEMBL9222166 | 0.77 | MRGPRX4 (0.42) | RXFP1RAB9ANPC1 | |
| SCHEMBL8948915 | 0.75 | MTNR1A (0.45) | MTNR1ARRM1L3MBTL1NR4A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525516-B1 | Derivatives of beta substituted cinnomic acid | BASF AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0525516-A2 | Derivatives of beta substituted cinnomic acid | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | disclosed |