Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949014 | 0.91 | NR4A2 (0.43) | NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A | |
| SCHEMBL8949021 | 0.91 | NR4A2 (0.43) | NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A | |
| SCHEMBL8949018 | 0.91 | NR4A2 (0.43) | NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A | |
| SCHEMBL9218125 | 0.83 | MTNR1A (0.44) | NR4A2MTNR1APLAUPLK1 | |
| SCHEMBL9222769 | 0.82 | MTNR1A (0.43) | NR4A2MTNR1APLAUMTNR1BPLK1 | |
| SCHEMBL9213636 | 0.82 | MTNR1A (0.43) | NR4A2MTNR1APLAUMTNR1BPLK1 | |
| SCHEMBL9222166 | 0.80 | MRGPRX4 (0.42) | SMN1; SMN2 | |
| SCHEMBL9213563 | 0.80 | MRGPRX4 (0.42) | SMN1; SMN2 | |
| SCHEMBL10552187 | 0.76 | NR4A2 (0.41) | NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A | |
| SCHEMBL10552181 | 0.76 | NR4A2 (0.41) | NR4A2ALDH1A1HPGDSMN1; SMN2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525516-B1 | Derivatives of beta substituted cinnomic acid | BASF AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0525516-A2 | Derivatives of beta substituted cinnomic acid | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | disclosed |