Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218314 | 0.82 | TLR7 (0.62) | MEN1KMT2ATLR7TP53PDE10A | |
| SCHEMBL9207843 | 0.78 | CYP1A2 (0.51) | POLBHTTMEN1KMT2ATLR7 | |
| SCHEMBL18998174 | 0.76 | SMN1; SMN2 (0.53) | MEN1KMT2ATLR7SMN1; SMN2PIK3CA | |
| SCHEMBL9216070 | 0.74 | PIK3CA (0.49) | POLBMEN1KMT2ATLR7LMNA | |
| Ammonia Solution, Strong SCHEMBL28506046 | 0.73 | PIK3CA (0.48) | POLBMEN1KMT2ATLR7LMNA | |
| SCHEMBL9838503 | 0.72 | PDE10A (0.40) | TLR7SMN1; SMN2LMNAMAPTPDE10A | |
| SCHEMBL9212879 | 0.71 | ALDH1A1 (0.52) | POLBHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9601950 | 0.70 | PDE10A (0.47) | MEN1KMT2ATLR7PIK3CAMTOR | |
| SCHEMBL18998178 | 0.70 | KDM4E (0.54) | POLBMEN1KMT2ATLR7SMN1; SMN2 | |
| SCHEMBL9601962 | 0.68 | PDE10A (0.42) | POLBMEN1KMT2ATLR7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |