Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771954 | 0.91 | TLR7 (0.54) | TLR7 | |
| SCHEMBL9838302 | 0.81 | TLR7 (0.62) | TLR7 | |
| SCHEMBL9212879 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1NPC1LMNAMAPT | |
| SCHEMBL9218314 | 0.76 | TLR7 (0.62) | PDE10ATLR7KDM4EALDH1A1NPC1 | |
| SCHEMBL9216070 | 0.74 | PIK3CA (0.49) | PDE10ATLR7CYP1A2KDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28506046 | 0.73 | PIK3CA (0.48) | PDE10ATLR7CYP1A2KDM4EALDH1A1 | |
| SCHEMBL9213565 | 0.72 | POLB (0.50) | PDE10ATLR7LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9601950 | 0.70 | PDE10A (0.47) | PDE10ATLR7CYP1A2KDM4ENPC1 | |
| SCHEMBL18998174 | 0.70 | SMN1; SMN2 (0.53) | PDE10ATLR7CYP1A2KDM4ENPC1 | |
| SCHEMBL18998178 | 0.70 | KDM4E (0.54) | PDE10ATLR7CYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223420-B1 | CONDENSED IMIDAZOPYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0223420-A1 | Condensed imidazopyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |