Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838503 | 0.79 | PDE10A (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDTSHR | |
| SCHEMBL9218314 | 0.79 | TLR7 (0.62) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL9212191 | 0.76 | LMNA (0.50) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL9216070 | 0.76 | PIK3CA (0.49) | ALDH1A1KDM4EHSD17B10TP53MAPT | |
| Ammonia Solution, Strong SCHEMBL28506046 | 0.75 | PIK3CA (0.48) | ALDH1A1KDM4EHSD17B10TP53MAPT | |
| SCHEMBL4622963 | 0.75 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL18998174 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL18998178 | 0.72 | KDM4E (0.54) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 | |
| SCHEMBL9601950 | 0.72 | PDE10A (0.47) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9207843 | 0.72 | CYP1A2 (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |