Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206767 | 0.91 | KDM4E (0.49) | ADRB2ARHTR7FYNTP53 | |
| SCHEMBL5310309 | 0.90 | KDM4E (0.51) | ADRB2ARHTR7FYNTP53 | |
| SCHEMBL1046904 | 0.90 | KDM4E (0.51) | ADRB2ARHTR7FYNTP53 | |
| SCHEMBL28337685 | 0.90 | KDM4E (0.51) | ADRB2ARHTR7FYNTP53 | |
| SCHEMBL12958318 | 0.84 | IDO1 (0.48) | ADRB2ARHTR7FYNTP53 | |
| Water SCHEMBL27583143 | 0.83 | ADRB2 (0.65) | ADRB2HTR7TP53MAPK1RAB9A | |
| SCHEMBL9213631 | 0.82 | CYP11B1 (0.61) | ADRB2ARHTR7TP53MAPK1 | |
| SCHEMBL15522393 | 0.82 | AR (0.51) | ARHTR7FYNTP53MAPK1 | |
| SCHEMBL27301114 | 0.82 | ADRB2 (0.63) | ADRB2HTR7TP53MAPK1RAB9A | |
| SCHEMBL1389258 | 0.81 | ADRB2 (0.67) | ADRB2HTR7TP53MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2691393-B1 | NOVEL BICYCLIC PYRIDINONES | PFIZER (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9067934-B2 | Bicyclic pyridinones | PFIZER INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20140045790-A1 | Novel Bicyclic Pyridinones | PFIZER INC. (US) | 2014-02-13 | — | — | US | disclosed |
| EP-0180592-B1 | LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX | UNIV KENT STATE OHIO (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0238626-B1 | LIQUID CRYSTAL LIGHT-MODULATING MATERIALS | UNIV KENT STATE OHIO (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0202341-B1 | DICHROIC AZO DYES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-03-28 | — | — | EP | disclosed |
| US-4734218-A | COLOR DISPLAY | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0202341-A1 | DICHROIC AZO DYES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045790-A1 | Novel Bicyclic Pyridinones | CYP2B6, CYP2C19, CYP2D6 | ADRB2 355/4885AR 2670/4885HTR7 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.