SCHEMBL1389258

SCHEMBL1389258

CCCOc1ccccc1-c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.67
HTR7 P34969 1/20 0.66
TP53 P04637 1/20 0.65
MAPK1 P28482 1/20 0.65
RAB9A P51151 1/20 0.65
ADRB1 P08588 2/20 0.58
KDM4E B2RXH2 8/20 0.57
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
LMNA P02545 2/20 0.54
PKM P14618 1/20 0.52
KMT2A Q03164 1/20 0.52
HTT P42858 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27583143 0.98 ADRB2 (0.65) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL27301114 0.96 ADRB2 (0.63) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL10706756 0.90 ADRB2 (0.65) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL7638760 0.89 ADRB2 (0.63) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL34465293 0.89 ADRB2 (0.63) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL27528318 0.88 ADRB2 (0.54) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL13739595 0.87 TP53 (0.74) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL10438816 0.87 HTR7 (0.53) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL15473193 0.87 ADRB2 (0.53) ADRB2HTR7TP53MAPK1RAB9A
SCHEMBL10434829 0.87 ADRB2 (0.61) ADRB2HTR7TP53MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113511987-A Chiral photosensitive dopant and preparation method and application thereof 华南师范大学 2021-10-19 CN claimed
CN-109053387-B Method for synthesizing magnolol 九江学院 2021-07-09 CN claimed
CN-106928283-B Carbazole and the double modifications of phosphine oxygen are coordinated phenylbenzimidazol complex of iridium, preparation method and applications 黑龙江大学 2019-05-07 CN claimed
CN-106928283-A Carbazole and the double modifications of phosphine oxygen coordination phenylbenzimidazol complex of iridium, preparation method and applications 黑龙江大学 2017-07-07 CN claimed
CN-104769000-A Epoxy resin mixture, epoxy resin composition, and cured product thereof NIPPON KAYAKU KK 2015-07-08 CN claimed
CN-102648236-A Anaerobically compostable polymeric compositions, articles and landfill biodegradation BIOTECH PRODUCTS LLC 2012-08-22 CN claimed
CN-1245382-C 4'-methanesulfonyl-biphenyl derivatives as a highly selective cyclooxygenase-2 inhibitor CHEIL JEDANG CORP (KR) 2006-03-15 CN claimed
CN-1568309-A 4'-methanesulfonyl-biphenyl derivatives as a highly selective cyclooxygenase-2 inhibitor CHEIL JEDANG CORP (KR) 2005-01-19 CN claimed
US-12516039-B2 N-linked isoquinoline amides as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof MERCK SHARP & DOHME LLC (US) 2026-01-06 US disclosed
US-20250177408-A1 INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Etern Therapeutics Hongkong Limited (CN) 2025-06-05 US disclosed
EP-4536356-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS Xenon Pharmaceuticals Inc. (CA) 2025-04-16 EP disclosed
US-20240254095-A1 NMDA Receptor Antagonist and Use Thereof SYNPHATEC (SHANGHAI) BIOPHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2024-08-01 US disclosed
US-20240109887-A1 NOVEL SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AS SOS1 INHIBITORS VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) 2024-04-04 US disclosed
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE AMGEN INC. 2024-02-22 US disclosed
CN-1245382-C 4'-methanesulfonyl-biphenyl derivatives as a highly selective cyclooxygenase-2 inhibitor CHEIL JEDANG CORP (KR) 2006-03-15 CN disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
CN-1568309-A 4'-methanesulfonyl-biphenyl derivatives as a highly selective cyclooxygenase-2 inhibitor CHEIL JEDANG CORP (KR) 2005-01-19 CN disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed
EP-0141656-B1 IMPREGNATED CAPACITOR TORAY INDUSTRIES, INC. (JP) 1988-06-01 EP disclosed
EP-0141656-A1 Impregnated capacitor TORAY INDUSTRIES, INC. (JP) 1985-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254095-A1 NMDA Receptor Antagonist and Use Thereof GRIN2B, GRIN1, GRIN3A ADRB2 365/4885HTR7 378/4885TP53 3024/4885
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE KRAS, HRAS, APC ADRB2 4139/4885HTR7 4466/4885TP53 6/4885
US-20240109887-A1 NOVEL SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AS SOS1 INHIBITORS SOS1, SOS2, KSR1 ADRB2 4150/4885HTR7 4737/4885TP53 111/4885
US-20250177408-A1 INHIBITOR OF INTERACTION BETWEEN YAP/TAZ AND TEAD, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF YAP1, YES1, TEAD2 ADRB2 4507/4885HTR7 4268/4885TP53 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.