Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845291 | 0.83 | LMNA (0.41) | ALDH1A1GSK3BPTPN1KMT2AMEN1 | |
| SCHEMBL9203574 | 0.82 | TSHR (0.50) | ALDH1A1ANPEP | |
| SCHEMBL7640651 | 0.78 | LMNA (0.31) | CYP2D6CYP2C9CYP2C19ESR1 | |
| SCHEMBL1597293 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GSK3BKMT2AMEN1CYP2C9 | |
| SCHEMBL20587670 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ESR1 | |
| SCHEMBL68148 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ESR1 | |
| SCHEMBL6441255 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CYP2C9ANPEPHDAC8HDAC6 | |
| SCHEMBL9681747 | 0.72 | ALDH1A1 (0.45) | ALDH1A1GSK3BKMT2AMEN1CYP2C9 | |
| SCHEMBL9370511 | 0.72 | TSHR (0.42) | GSK3BKMT2AMEN1CYP2D6CYP2C9 | |
| SCHEMBL10915629 | 0.72 | ESR1 (0.50) | ALDH1A1PTPN1KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216624-B1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-02-22 | — | — | EP | disclosed |
| US-5371075-A | Pesticides | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |
| US-5157029-A | Insecticides, miticides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-10-20 | — | — | US | disclosed |
| US-5057508-A | Bicyclo(2-2-1)octanes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-10-15 | — | — | US | disclosed |
| US-4965257-A | INSECTICIDES, ACARICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-10-23 | — | — | US | disclosed |
| US-4772624-A | INSECTICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0216624-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-04-01 | — | — | EP | disclosed |