Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884759 | 0.76 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9200963 | 0.76 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9270932 | 0.75 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9218169 | 0.75 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9220790 | 0.73 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884646 | 0.73 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5883897 | 0.73 | LMNA (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5884679 | 0.73 | LMNA (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5884554 | 0.73 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884597 | 0.72 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320032-B1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-01-18 | — | — | EP | disclosed |
| US-5231184-A | Viricide intermediate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-27 | — | — | US | disclosed |
| US-5106973-A | Viricide intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-21 | — | — | US | disclosed |
| US-4992433-A | Viricides | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-12 | — | — | US | disclosed |
| EP-0320032-A1 | Pyridizinamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-06-14 | — | — | EP | disclosed |