Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 7/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212333 | 0.86 | MAPT (0.46) | LDHALDHBMCL1MAPTKDM4E | |
| SCHEMBL9212264 | 0.82 | KDM4E (0.55) | LDHALDHBMAPTKDM4EMEN1 | |
| SCHEMBL9209330 | 0.81 | ANO1 (0.43) | LDHALDHBMAPTKDM4EMEN1 | |
| SCHEMBL9221063 | 0.81 | ANO1 (0.43) | LDHALDHBMAPTKDM4EMEN1 | |
| SCHEMBL9210214 | 0.81 | MAPT (0.54) | MCL1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9212129 | 0.81 | L3MBTL1 (0.45) | MEN1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9213858 | 0.79 | L3MBTL1 (0.49) | MCL1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9220326 | 0.76 | MAPT (0.54) | MCL1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9220502 | 0.76 | MCL1 (0.51) | MCL1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL9219801 | 0.75 | MCL1 (0.42) | MCL1MAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |