Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 7/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212406 | 0.92 | L3MBTL1 (0.53) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9213695 | 0.88 | L3MBTL1 (0.46) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9219551 | 0.88 | L3MBTL1 (0.46) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9220347 | 0.88 | NAAA (0.49) | L3MBTL1HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9218058 | 0.87 | L3MBTL1 (0.44) | L3MBTL1HPGDTP53ALDH1A1TSHR | |
| SCHEMBL9212117 | 0.82 | TP53 (0.51) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9216023 | 0.82 | L3MBTL1 (0.54) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9209891 | 0.81 | HPGD (0.45) | HPGDTP53ALDH1A1TSHR | |
| SCHEMBL9213874 | 0.81 | LDHA (0.43) | HPGDTP53SMN1; SMN2ALDH1A1PLK1 | |
| SCHEMBL9216814 | 0.81 | NAAA (0.50) | HPGDALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |