Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212323 | 0.87 | L3MBTL1 (0.51) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL8201626 | 0.83 | L3MBTL1 (0.60) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9209323 | 0.82 | L3MBTL1 (0.47) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9221054 | 0.82 | MAPT (0.54) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9210201 | 0.82 | MCL1 (0.57) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9212117 | 0.81 | TP53 (0.51) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9213874 | 0.79 | LDHA (0.43) | RAB9AKMT2AMEN1ALDH1A1MCL1 | |
| SCHEMBL9220492 | 0.76 | MCL1 (0.65) | RAB9AKMT2AMEN1ALDH1A1MCL1 | |
| SCHEMBL9219788 | 0.76 | MCL1 (0.50) | L3MBTL1KMT2AMEN1ALDH1A1MCL1 | |
| SCHEMBL9430605 | 0.75 | TP53 (0.71) | L3MBTL1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |