SCHEMBL9214296

SCHEMBL9214296

C=CC(=O)OCCc1ccsc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.47
TSHR P16473 5/20 0.47
ALDH1A1 P00352 3/20 0.47
TP53 P04637 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP3A4 P08684 1/20 0.43
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
HPGD P15428 2/20 0.40
GRM2 Q14416 1/20 0.39
GRM3 Q14832 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9903115 0.83 SLC1A3 (0.45) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL9806249 0.81 TSHR (0.59) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL23661935 0.80 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL23662058 0.80 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL13134277 0.79 THRB (0.62) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL723115 0.78 OPRM1 (0.47) TSHRALDH1A1OPRM1OPRD1OPRK1
SCHEMBL22195129 0.77 TSHR (0.59) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL1569426 0.77 AKR1B10 (0.72) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1569423 0.77 AKR1B10 (0.72) TSHRALDH1A1TP53HIF1AHSD17B10
Hydrochloric Acid SCHEMBL27528734 0.77 OPRM1 (0.46) ALDH1A1TP53OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112759996-B PEDOT/polyacrylate modified polythiophene antistatic material and preparation method thereof 江苏富琪森新材料有限公司 2022-03-15 CN claimed
CN-112759996-A PEDOT/polyacrylate modified polythiophene antistatic material and preparation method thereof 江苏富琪森新材料有限公司 2021-05-07 CN claimed
CN-112759996-B PEDOT/polyacrylate modified polythiophene antistatic material and preparation method thereof 江苏富琪森新材料有限公司 2022-03-15 CN disclosed
CN-112759996-A PEDOT/polyacrylate modified polythiophene antistatic material and preparation method thereof 江苏富琪森新材料有限公司 2021-05-07 CN disclosed
WO-2012076288-A1 COMPOSITE COMPRISING NANOPARTICLES AND METHOD OF MAKING NANOPARTICLES UNIVERSITE DE LIEGE (BE) 2012-06-14 WO disclosed
EP-2462898-A1 Composite comprising nanoparticles and method for making nanoparticles Université de Liège (BE) 2012-06-13 EP disclosed
CN-100356917-C Carboxylic and substituted oxazole derivatives for use as PPAR-& and PPAR-r activators in the treatment of diabetes HOFFMANN LA ROCHE (CH) 2007-12-26 CN disclosed
CN-1509173-A Carboxylic and substituted oxazole derivatives for use as PPAR-& and PPAR-r activators in the treatment of diabetes - 2004-06-30 CN disclosed
WO-1995000882-A1 SOLUBLE, CONDUCTIVE COPOLYMER, THE PREPARATION AND USE THEREOF NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1995-01-05 WO disclosed