Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451685 | 0.87 | CHRNA1 (0.34) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9451535 | 0.84 | SLC6A4 (0.38) | CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL9451674 | 0.82 | BACE1 (0.32) | — | |
| SCHEMBL23117237 | 0.79 | PNMT (0.41) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9212549 | 0.78 | CYP2C9 (0.42) | CYP2C9CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL9208402 | 0.78 | KDM4E (0.41) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9205348 | 0.78 | — | — | |
| SCHEMBL9208191 | 0.78 | ADK (0.31) | — | |
| SCHEMBL18084692 | 0.77 | PGR (0.33) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9451477 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216624-B1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-02-22 | — | — | EP | disclosed |
| US-5371075-A | Pesticides | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |
| US-5157029-A | Insecticides, miticides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-10-20 | — | — | US | disclosed |
| US-5057508-A | Bicyclo(2-2-1)octanes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-10-15 | — | — | US | disclosed |
| US-4965257-A | INSECTICIDES, ACARICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0216624-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-04-01 | — | — | EP | disclosed |