Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4325783 | 0.98 | ALDH1A1 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4337073 | 0.98 | SMN1; SMN2 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4337065 | 0.98 | SMN1; SMN2 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4953807 | 0.98 | ALDH1A1 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL7485551 | 0.94 | ALDH1A1 (0.37) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4333124 | 0.94 | ALDH1A1 (0.44) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL9202745 | 0.92 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4954390 | 0.92 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4325752 | 0.92 | SMN1; SMN2 (0.44) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL9214644 | 0.92 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| EP-2616458-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| EP-2616459-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-8609700-B2 | Pyridine compounds for controlling invertebrate pests I | BASF SE (DE) | 2013-12-17 | — | — | US | disclosed |
| EP-2648518-A2 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-10-16 | — | — | EP | disclosed |
| US-20130253012-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2616459-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2616458-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034959-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012034961-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012034960-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011063277-A1 | ANTI-ORAI1 ANTIGEN BINDING PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2011-05-26 | — | — | WO | disclosed |
| EP-0742218-B1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO CO (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6063782-A | Pyrrolopyridazine derivatives | SANKYO COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0742218-A1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | PRXL2A, NR2C2, SHROOM3 | ALDH1A1 1345/4885ALOX15 3430/4885SMN1; SMN2 901/4885 |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | PRXL2A, SHROOM3, NR2C2 | ALDH1A1 1331/4885ALOX15 3284/4885SMN1; SMN2 854/4885 |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | GRIN2A, NR2C2, GRIA2 | ALDH1A1 1480/4885ALOX15 3334/4885SMN1; SMN2 1356/4885 |
| US-20130253012-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | RTN3, RRS1, RTF1 | ALDH1A1 3516/4885ALOX15 1601/4885SMN1; SMN2 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.