Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213416 | 0.73 | KMT2A (0.68) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| Xanthone SCHEMBL28434710 | 0.71 | MAOA (0.95) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL9206022 | 0.71 | KMT2A (0.61) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL10511892 | 0.70 | TBK1 (0.76) | KMT2AMEN1KDM4ERAB9ANPC1 | |
| SCHEMBL22649967 | 0.70 | TTR (0.52) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL22650130 | 0.70 | TTR (0.52) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL22171892 | 0.70 | KDM4E (0.60) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL16477273 | 0.70 | MAOA (0.60) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL24299383 | 0.70 | TTR (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL28557548 | 0.69 | MEN1 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | claimed |
| EP-0561845-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES. | BASF AG (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010500-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | disclosed |