Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213416 | 0.85 | KMT2A (0.68) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL17072179 | 0.76 | KMT2A (0.81) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL9837713 | 0.74 | MAOA (0.61) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL12983484 | 0.73 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL16477274 | 0.73 | MAOA (0.67) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL14701609 | 0.72 | TTR (0.58) | KMT2AMEN1KDM4ECYP3A4RECQL | |
| SCHEMBL9214814 | 0.71 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1KDM4E | |
| Xanthone SCHEMBL11245548 | 0.71 | MAOA (0.86) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL9836819 | 0.71 | MAOA (0.61) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL9214682 | 0.71 | KMT2A (0.54) | KMT2AMEN1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | claimed |
| EP-0561845-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES. | BASF AG (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010500-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | disclosed |