SCHEMBL921487

SCHEMBL921487

COCc1ccc(C(=O)NCc2cccc(Oc3cccc(C(F)(F)F)c3)c2)c(N)n1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.51
PPARD Q03181 10/20 0.51
PPARA Q07869 10/20 0.51
MAPK14 Q16539 1/20 0.50
HPGD P15428 2/20 0.45
RECQL P46063 1/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
KCNQ3 O43525 1/20 0.45
KCNQ2 O43526 1/20 0.45
LMNA P02545 1/20 0.44
DHFR P00374 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920735 0.94 PPARG (0.52) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL920726 0.94 RECQL (0.51) PPARGPPARDPPARAMAPK14RECQL
SCHEMBL919789 0.89 PPARG (0.53) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL920645 0.89 KDM4E (0.53) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL921027 0.88 MAPK14 (0.54) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL921647 0.88 HPGD (0.47) PPARGPPARDPPARAHPGDKDM4E
SCHEMBL921463 0.88 HPGD (0.57) PPARGPPARDPPARAHPGDKDM4E
SCHEMBL920127 0.87 KDM4E (0.47) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL920214 0.87 HPGD (0.48) PPARGPPARDPPARAHPGDKDM4E
SCHEMBL919552 0.87 HPGD (0.53) PPARGPPARDPPARAHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARG 391/4885PPARD 360/4885PPARA 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.