Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223545 | 1.00 | KDM4E (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL9214882 | 1.00 | KDM4E (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL15080558 | 0.88 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL13519732 | 0.88 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL17574398 | 0.87 | ACACB (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28173828 | 0.87 | ACACB (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL9073870 | 0.85 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL17574380 | 0.85 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL7299678 | 0.85 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL15533902 | 0.83 | LMNA (0.44) | ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |