Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7373363 | 0.89 | SLC15A1 (0.50) | SLC15A1MMP9ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8978262 | 0.85 | SLC15A1 (0.53) | SLC15A1MMP9SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9222366 | 0.83 | MMP9 (0.46) | SLC15A1MMP9SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9222177 | 0.83 | MMP9 (0.46) | SLC15A1MMP9SMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL3019993 | 0.83 | ACE (0.51) | SLC15A1MMP9ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24235709 | 0.80 | POLB (0.48) | SLC15A1SMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7295520 | 0.80 | SYK (0.53) | MAPK1L3MBTL1POLBCTSLCTSS | |
| SCHEMBL9217103 | 0.80 | SYK (0.53) | MAPK1L3MBTL1POLBCTSLCTSS | |
| SCHEMBL14195227 | 0.80 | ALDH1A1 (0.54) | SLC15A1MMP9ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24235691 | 0.78 | POLB (0.49) | SLC15A1SMN1; SMN2ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |