SCHEMBL9214976

SCHEMBL9214976

N#Cc1c(Br)c(C(F)(F)F)n(C(=O)c2ccc(Cl)c(Cl)c2)c1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.38
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
CRHBP P24387 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
CRHR2 Q13324 1/20 0.35
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
BIRC5 O15392 2/20 0.33
KDM1A O60341 1/20 0.33
PTGS2 P35354 1/20 0.33
HSD11B1 P28845 1/20 0.32
PKM P14618 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218224 0.91 MEN1 (0.37) PGRHPGDKDM4EMEN1ALDH1A1
SCHEMBL9423419 0.88 ALDH1A1 (0.38) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL9215790 0.87 MGLL (0.42) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL9218441 0.86 MGLL (0.37) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL8404970 0.86 ABCB1 (0.37) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL9217898 0.86 MGLL (0.41) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL9212106 0.86 PGR (0.36) PGRHPGDKDM4EMEN1ALDH1A1
SCHEMBL9218216 0.84 GRIA4 (0.40) MEN1KMT2APOLBPTGS2MGLL
SCHEMBL9423380 0.84 S1PR3 (0.34) HPGDKDM4EMEN1ALDH1A1LMNA
SCHEMBL9209300 0.83 MEN1 (0.42) PGRHPGDMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484614-B1 N-acylated arylpyrroles useful as insecticidal, acaricidal, nematicidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1995-05-24 EP claimed
US-5328928-A Miticides, nematocides, fungicides or molluscicides AMERICAN CYANAMID COMPANY (US) 1994-07-12 US claimed
US-5328928-A Miticides, nematocides, fungicides or molluscicides AMERICAN CYANAMID COMPANY (US) 1994-07-12 US disclosed