Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213989 | 0.91 | GCGR (0.37) | GCGRMEN1KMT2AKDM4ETBXAS1 | |
| SCHEMBL9215196 | 0.91 | GCGR (0.35) | GCGRMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9213982 | 0.85 | GCGR (0.36) | GCGRMEN1KMT2AKDM4ETBXAS1 | |
| SCHEMBL9312641 | 0.67 | TBXAS1 (0.37) | MEN1KMT2AKDM4ESMN1; SMN2TBXAS1 | |
| SCHEMBL9313258 | 0.67 | FFAR1 (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8027272 | 0.66 | HTR2A (0.60) | KDM4EOPRK1TSHRALDH1A1 | |
| SCHEMBL18055963 | 0.66 | HTR2A (0.60) | KDM4EOPRK1TSHRALDH1A1 | |
| SCHEMBL6837412 | 0.66 | HTR2A (0.60) | KDM4EOPRK1TSHRALDH1A1 | |
| SCHEMBL9218481 | 0.62 | PTK2 (0.38) | MEN1KMT2AKDM4ETBXAS1 | |
| SCHEMBL9218877 | 0.61 | HDAC3 (0.54) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |