Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213989 | 0.93 | GCGR (0.37) | GCGRMEN1KMT2AMAPK14LMNA | |
| SCHEMBL9215196 | 0.93 | GCGR (0.35) | GCGRMEN1KMT2AMAPK14TSHR | |
| SCHEMBL9215200 | 0.85 | GCGR (0.38) | GCGRMEN1KMT2AMAPK14LMNA | |
| SCHEMBL9209687 | 0.80 | TBXAS1 (0.36) | MEN1KMT2AMAPTFFAR2TBXAS1 | |
| SCHEMBL9215653 | 0.79 | FFAR1 (0.47) | MEN1KMT2A | |
| SCHEMBL23987343 | 0.76 | NR4A2 (0.40) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9312295 | 0.75 | TBXAS1 (0.34) | MEN1KMT2AMAPTTBXAS1KDM4E | |
| SCHEMBL9215423 | 0.74 | PTK2 (0.36) | MEN1KMT2AMAPTTBXAS1KDM4E | |
| SCHEMBL9218225 | 0.74 | ALDH1A1 (0.37) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL9220655 | 0.73 | MAPT (0.41) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | claimed |
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | disclosed |