Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213982 | 0.93 | GCGR (0.36) | GCGRMEN1KMT2AMAPK14LMNA | |
| SCHEMBL9215200 | 0.91 | GCGR (0.38) | GCGRMEN1KMT2AMAPK14LMNA | |
| SCHEMBL9215196 | 0.86 | GCGR (0.35) | GCGRMEN1KMT2AMAPK14TSHR | |
| SCHEMBL9312641 | 0.79 | TBXAS1 (0.37) | MEN1KMT2AMAPTFFAR2TBXAS1 | |
| SCHEMBL9313258 | 0.78 | FFAR1 (0.48) | MEN1KMT2A | |
| SCHEMBL9314703 | 0.74 | TBXAS1 (0.35) | MEN1KMT2APOLBMAPTTBXAS1 | |
| SCHEMBL9218481 | 0.73 | PTK2 (0.38) | MEN1KMT2AMAPTTBXAS1KDM4E | |
| SCHEMBL9313234 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL9312321 | 0.72 | MAPT (0.42) | LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL9220938 | 0.71 | MTNR1A (0.49) | MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |