Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9215204 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BTMPRSS6F2F7 | |
| Iodide SCHEMBL9223621 | 0.90 | MAPT (0.43) | ITGB3ITGA2BKDM4EMAPTNPSR1 | |
| SCHEMBL7304706 | 0.86 | ABCB1 (0.44) | MAPTNPSR1MMP1MMP3MMP9 | |
| SCHEMBL7296817 | 0.86 | MAPT (0.44) | ITGB3ITGA2BF2MAPTTDP1 | |
| Iodide SCHEMBL9221941 | 0.85 | CCKBR (0.43) | ITGB3ITGA2BF2MAPTTDP1 | |
| Iodide SCHEMBL9217545 | 0.84 | CCKBR (0.42) | ITGB3ITGA2BF7MAPTTDP1 | |
| SCHEMBL9866104 | 0.83 | MAPT (0.44) | ITGB3ITGA2BF2KDM4EMAPT | |
| SCHEMBL7321034 | 0.82 | ITGB3 (0.52) | ITGB3ITGA2BTMPRSS6F2 | |
| Iodide SCHEMBL9866079 | 0.82 | MAPT (0.43) | ITGB3ITGA2BF2KDM4EMAPT | |
| SCHEMBL9215140 | 0.82 | REN (0.47) | F2MAPTNPSR1TDP1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |