Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559821 | 0.88 | KDM4E (0.37) | GAATSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9630611 | 0.81 | GABRP (0.42) | TSHRSMN1; SMN2MEN1CYP3A4KMT2A | |
| SCHEMBL10676049 | 0.81 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2MEN1CYP3A4KMT2A | |
| SCHEMBL9317147 | 0.80 | ALDH1A1 (0.33) | KDM4EPOLB | |
| SCHEMBL9217725 | 0.77 | RAB9A (0.43) | GAATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4714308 | 0.73 | KLKB1 (0.40) | KMT2AL3MBTL1PPARA | |
| SCHEMBL2805203 | 0.73 | MGAM (0.40) | MEN1KMT2AL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL8660093 | 0.71 | ALDH1A1 (0.40) | GAATSHRSMN1; SMN2CYP3A4L3MBTL1 | |
| SCHEMBL9589132 | 0.71 | GABRP (0.40) | GAAMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL29619789 | 0.71 | DHODH (0.44) | GAATSHRSMN1; SMN2CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254951-B1 | 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID CO (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5334576-A | Pre- and postemergence | AMERICAN CYANAMID COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0254951-A2 | 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |