Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728774 | 0.82 | EGFR (0.38) | EGFRLMNARPS6KB1 | |
| SCHEMBL9729031 | 0.79 | EGFR (0.36) | EGFRLMNARPS6KB1 | |
| SCHEMBL9212072 | 0.78 | EGFR (0.36) | EGFRRPS6KB1 | |
| SCHEMBL9729048 | 0.72 | EGFR (0.50) | NR2F2GALR3EGFRLMNAPOLB | |
| SCHEMBL9212840 | 0.72 | ALDH1A1 (0.35) | EGFRRPS6KB1 | |
| SCHEMBL9208274 | 0.71 | PIK3CD (0.34) | EGFRRPS6KB1 | |
| SCHEMBL13283199 | 0.69 | GALR3 (0.63) | NR2F2GALR3EGFRLMNAPOLB | |
| SCHEMBL4572178 | 0.69 | GALR3 (0.63) | NR2F2GALR3EGFRLMNAPOLB | |
| SCHEMBL9729004 | 0.68 | IDH1 (0.39) | NR2F2GALR3EGFRKDR | |
| SCHEMBL8504743 | 0.67 | GALR3 (0.61) | NR2F2GALR3EGFRLMNARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370704-B1 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0370704-A2 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |