Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 12/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728933 | 0.90 | IDH1 (0.37) | IDH1EGFRGALR3NR2F2CRHR1 | |
| SCHEMBL9728735 | 0.84 | EGFR (0.39) | IDH1EGFRGALR3NR2F2CRHR1 | |
| SCHEMBL9729816 | 0.84 | EGFR (0.40) | IDH1EGFRGALR3NR2F2KRAS | |
| SCHEMBL9728675 | 0.79 | EGFR (0.39) | IDH1EGFRGALR3NR2F2KRAS | |
| SCHEMBL9212072 | 0.77 | EGFR (0.36) | EGFRCRHR1 | |
| SCHEMBL9208342 | 0.76 | RAB9A (0.63) | EGFR | |
| SCHEMBL9728774 | 0.74 | EGFR (0.38) | EGFRCRHR1 | |
| SCHEMBL15684929 | 0.73 | CNR1 (0.48) | IDH1EGFR | |
| SCHEMBL9729823 | 0.71 | EGFR (0.39) | IDH1EGFRGALR3NR2F2CRHR1 | |
| SCHEMBL9212840 | 0.71 | ALDH1A1 (0.35) | EGFRCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | claimed |