Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220132 | 0.91 | CA12 (0.35) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL9221928 | 0.90 | MAPT (0.34) | MAPTRXFP1THRBCA12CA1 | |
| SCHEMBL9219360 | 0.89 | NPSR1 (0.37) | MAPTRXFP1THRBCA12CA1 | |
| SCHEMBL9218094 | 0.89 | MAPT (0.35) | MAPTRXFP1THRBCA12CA1 | |
| SCHEMBL9217235 | 0.81 | NPSR1 (0.35) | MAPTTHRBCA12CA1CA2 | |
| SCHEMBL9222097 | 0.79 | NPSR1 (0.34) | MAPTTHRBCA12CA1CA2 | |
| SCHEMBL9217189 | 0.79 | ABCC9 (0.34) | MAPTTHRBCA12CA1CA2 | |
| SCHEMBL7466977 | 0.79 | AVPR1A (0.39) | MAPTRXFP1MEN1KMT2ALMNA | |
| Water SCHEMBL8742785 | 0.79 | AVPR1B (0.39) | MAPTRXFP1MEN1KMT2ALMNA | |
| Water SCHEMBL8589898 | 0.79 | AVPR1B (0.39) | MAPTRXFP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |