SCHEMBL9215445

SCHEMBL9215445

CS(=O)(=O)NC1CCC(CO)CC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA7 P43166 2/20 0.41
CA14 Q9ULX7 2/20 0.41
HTR2A P28223 9/20 0.34
DRD3 P35462 9/20 0.34
DRD2 P14416 8/20 0.34
HTR1A P08908 1/20 0.34
PIK3CD O00329 2/20 0.32
PIK3CG P48736 2/20 0.32
CA1 P00915 1/20 0.32
PIK3CB P42338 1/20 0.32
G6PD P11413 1/20 0.32
PGR P06401 1/20 0.32
PIK3C3 Q8NEB9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12017973 1.00 CA12 (0.41) CA12CA7CA14HTR2ADRD3
SCHEMBL12017965 1.00 CA12 (0.41) CA12CA7CA14HTR2ADRD3
SCHEMBL7705222 0.82 INPP5A (0.37)
SCHEMBL48337 0.82
SCHEMBL15836240 0.82 CA12 (0.58) CA12CA7CA14CA1PGR
SCHEMBL19694135 0.82 SMYD3 (0.40) CA12CA7CA14HTR2ADRD3
SCHEMBL19694137 0.82 SMYD3 (0.40) CA12CA7CA14HTR2ADRD3
SCHEMBL8294594 0.81 CA12 (0.42) CA12CA7CA14HTR2ADRD3
SCHEMBL8201280 0.81 CA12 (0.42) CA12CA7CA14HTR2ADRD3
SCHEMBL15014471 0.81 CA12 (0.42) CA12CA7CA14HTR2ADRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616682-B2 1-H-pyrrolo[2,3-c]pyridine compounds ACERTA PHARMA B.V. (NL) 2026-05-05 US disclosed
EP-4688776-A1 1-H-PYRROLO[2,3-C]PYRIDINE COMPOUNDS ACTING AGAINST CANCER VIA AGONISM OF MENIN Acerta Pharma B.V. (NL) 2026-02-11 EP disclosed
US-20250360112-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS ACERTA PHARMA BV (NL) 2025-11-27 US disclosed
US-20240335431-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS ACERTA PHARMA B.V. (NL) 2024-10-10 US disclosed
WO-2024201240-A1 1-H-PYRROLO[2,3-C]PYRIDINE COMPOUNDS ACTING AGAINST CANCER VIA AGONISM OF MENIN ACERTA PHARMA B.V. (NL) 2024-10-03 WO disclosed
EP-0444549-B1 Imidazopyridazines their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-01-25 EP disclosed
US-5145850-A Antiasthmatic TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-08 US disclosed
EP-0444549-A1 Imidazopyridazines their production and use Takeda Chemical Industries, Ltd. (JP) 1991-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616682-B2 1-H-pyrrolo[2,3-c]pyridine compounds MEN1, PKD1, PKD2 CA12 2284/4885CA7 2003/4885CA14 2320/4885
US-20240335431-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS MEN1, PKD1, ADCYAP1R1 CA12 3994/4885CA7 2601/4885CA14 4071/4885
US-20250360112-A1 1-H-PYRROLO[2,3-c]PYRIDINE COMPOUNDS MEN1, PKD1, ADCYAP1R1 CA12 3994/4885CA7 2601/4885CA14 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.