Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626034 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL3709128 | 0.85 | — | — | |
| SCHEMBL4896327 | 0.80 | CA1 (0.33) | INPP5A | |
| SCHEMBL22576810 | 0.78 | DGAT1 (0.31) | INPP5A | |
| SCHEMBL1795365 | 0.77 | CA2 (0.37) | — | |
| SCHEMBL636443 | 0.77 | — | — | |
| SCHEMBL3226350 | 0.76 | DGAT1 (0.30) | — | |
| SCHEMBL231062 | 0.76 | GABRA5 (0.39) | CYP3A4 | |
| SCHEMBL21602919 | 0.75 | CA2 (0.41) | — | |
| SCHEMBL1044247 | 0.75 | CA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444549-B1 | Imidazopyridazines their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5145850-A | Antiasthmatic | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0444549-A1 | Imidazopyridazines their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-04 | — | — | EP | disclosed |