Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158265 | 0.82 | SIRT3 (0.41) | SIRT3TDP1NTRK1PIM1HSP90AA1 | |
| SCHEMBL23116461 | 0.82 | SIRT3 (0.41) | SIRT3TDP1NTRK1PIM1HSP90AA1 | |
| SCHEMBL1591434 | 0.82 | NTRK1 (0.33) | CDC7ALDH1A1NTRK1PIM1HSP90AA1 | |
| SCHEMBL24691980 | 0.82 | SIRT3 (0.41) | KDM4EL3MBTL1CDC7AKT1RPS6KB1 | |
| SCHEMBL4954933 | 0.82 | KDM4E (0.39) | KDM4EL3MBTL1CDC7AKT1RPS6KB1 | |
| Hydrochloric Acid SCHEMBL28042958 | 0.81 | GRIN3B (0.32) | CDC7NTRK1PIM1HSP90AA1 | |
| SCHEMBL23137500 | 0.81 | KDM4E (0.38) | KDM4EL3MBTL1CDC7AKT1RPS6KB1 | |
| SCHEMBL3429807 | 0.78 | PARP1 (0.53) | KDM4EL3MBTL1TDP1IRAK4PARP1 | |
| SCHEMBL14857136 | 0.76 | NTRK1 (0.43) | CDC7NTRK1PIM1HSP90AA1 | |
| SCHEMBL9002808 | 0.76 | SIRT3 (0.44) | KDM4EL3MBTL1CDC7SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422456-B1 | Pyridine derivatives and their use in combating unwanted plant growth | BASF AG (DE) | 1995-05-03 | — | — | EP | claimed |