SCHEMBL4954933

SCHEMBL4954933

CC(C)c1nccc(C(N)=O)c1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CDC7 O00311 1/20 0.38
AKT1 P31749 2/20 0.37
RPS6KB1 P23443 1/20 0.37
SIRT3 Q9NTG7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
IRAK4 Q9NWZ3 2/20 0.35
PARP1 P09874 1/20 0.35
PIK3CB P42338 1/20 0.35
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
AHR P35869 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215517 0.82 KDM4E (0.39) KDM4EL3MBTL1CDC7AKT1RPS6KB1
SCHEMBL24691980 0.82 SIRT3 (0.41) KDM4EL3MBTL1CDC7AKT1RPS6KB1
SCHEMBL23137500 0.81 KDM4E (0.38) KDM4EL3MBTL1CDC7AKT1RPS6KB1
SCHEMBL3429807 0.78 PARP1 (0.53) KDM4EL3MBTL1TDP1IRAK4PARP1
SCHEMBL2882576 0.76 IRAK4 (0.44) KDM4EL3MBTL1CDC7SIRT3TDP1
SCHEMBL2977145 0.72 IRAK4 (0.50) KDM4EIRAK4PARP1HTTALDH1A1
Phosphoric Acid SCHEMBL31729557 0.72 PARP1 (0.47) KDM4EL3MBTL1TDP1IRAK4PARP1
SCHEMBL1591434 0.71 NTRK1 (0.33) CDC7ALDH1A1HSP90AA1JAK2
SCHEMBL23116461 0.71 SIRT3 (0.41) SIRT3TDP1HSP90AA1
SCHEMBL31158265 0.71 SIRT3 (0.41) SIRT3TDP1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1691610-B1 METHOD FOR MODIFYING THE BEHAVIOUR OF THRIPS WITH PYRIDINE DERIVATIVES NZ INST PLANT & FOOD RES LTD (NZ) 2016-03-09 EP claimed
US-8962003-B2 Insect behaviour modifying compounds THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2015-02-24 US claimed
US-20080241205-A1 Insect Behaviour Modifying Compounds THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2008-10-02 US claimed
EP-1691610-A1 INSECT BEHAVIOUR MODIFYING COMPOUNDS New Zealand Institute for Crop & Food Research Limited and Plant Research International B.V. (NL) 2006-08-23 EP claimed
WO-2005046330-A1 INSECT BEHAVIOUR MODIFYING COMPOUNDS NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) 2005-05-26 WO claimed
CN-114831116-B Application of acetic acid phyllyl ester in preventing and treating meloidogyne incognita 浙江大学 2023-01-06 CN disclosed
CN-114831116-A Application of acetic acid leaf alcohol ester in preventing and treating meloidogyne incognita 浙江大学 2022-08-02 CN disclosed
EP-3031322-B1 COMPOSITION COMPRISING HARMFUL ARTHROPOD-ATTRACTING SUBSTANCE FORMED FROM PLANT-DERIVED COMPONENTS AND ANALOGS THEREOF KYOYU AGRI CO LTD (JP) 2019-09-11 EP disclosed
US-20160227776-A1 COMPOSITION CONTAINING ATTRACTANT OF NOXIOUS ARTHROPOD COMPRISING PLANT-DERIVED COMPONENT AND ANALOGUE OF SAME KYOYU AGRI CO., LTD. (JP) 2016-08-11 US disclosed
EP-3031322-A1 COMPOSITION COMPRISING HARMFUL ARTHROPOD-ATTRACTING SUBSTANCE FORMED FROM PLANT-DERIVED COMPONENTS AND ANALOGS THEREOF Kyoyu Agri Co. Ltd. (JP) 2016-06-15 EP disclosed
EP-1691610-B1 METHOD FOR MODIFYING THE BEHAVIOUR OF THRIPS WITH PYRIDINE DERIVATIVES NZ INST PLANT & FOOD RES LTD (NZ) 2016-03-09 EP disclosed
US-8962003-B2 Insect behaviour modifying compounds THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2015-02-24 US disclosed
US-20080241205-A1 Insect Behaviour Modifying Compounds THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2008-10-02 US disclosed
EP-1691610-A1 INSECT BEHAVIOUR MODIFYING COMPOUNDS New Zealand Institute for Crop & Food Research Limited and Plant Research International B.V. (NL) 2006-08-23 EP disclosed
WO-2005105814-A1 TETRACYCLIC INHIBITORS OF JANUS KINASES INCYTE CORPORATION (US) 2005-11-10 WO disclosed
WO-2005046330-A1 INSECT BEHAVIOUR MODIFYING COMPOUNDS NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) 2005-05-26 WO disclosed
EP-0578419-B1 Pyridine derivatives and pharmaceutical compositions containing them KYOWA HAKKO KOGYO KK (JP) 1996-09-04 EP disclosed
EP-0578419-A1 Pyridine derivatives and pharmaceutical compositions containing them KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241205-A1 Insect Behaviour Modifying Compounds PNMT, ACHE, THOP1 KDM4E 1017/4885L3MBTL1 10/4885CDC7 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.