Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205886 | 0.90 | PRMT5 (0.51) | PRMT5SIGMAR1 | |
| SCHEMBL9215629 | 0.88 | PRMT5 (0.38) | PRMT5SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9213421 | 0.85 | MEN1 (0.37) | PRMT5MAPTKDM2B | |
| Hydrochloric Acid SCHEMBL9215384 | 0.84 | PRMT5 (0.40) | PRMT5 | |
| SCHEMBL9210433 | 0.84 | PRMT5 (0.41) | PRMT5MAPTKDM2B | |
| SCHEMBL9212338 | 0.84 | RAB9A (0.40) | PRMT5SIGMAR1 | |
| SCHEMBL9206673 | 0.82 | PRMT5 (0.38) | PRMT5SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9206175 | 0.81 | PDE4B (0.40) | PRMT5SIGMAR1MAPT | |
| SCHEMBL9215245 | 0.80 | ALDH1A1 (0.41) | PRMT5SIGMAR1MAPT | |
| SCHEMBL9738736 | 0.80 | HTT (0.53) | PRMT5MAPTKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |