Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215547 | 0.80 | PRMT5 (0.44) | KDM2BPRMT5MAPT | |
| Hydrochloric Acid SCHEMBL9213421 | 0.80 | MEN1 (0.37) | HTTMEN1KMT2AKDM2BPRMT5 | |
| SCHEMBL9213097 | 0.79 | PDE4B (0.43) | HTTMEN1KMT2APRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL9206777 | 0.77 | HTT (0.52) | HTTMAPTTSHR | |
| Hydrochloric Acid SCHEMBL9206175 | 0.76 | PDE4B (0.40) | MEN1KMT2APRMT5MAPTTSHR | |
| Hydrochloric Acid SCHEMBL9213818 | 0.74 | HTT (0.55) | HTTMAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL9208157 | 0.73 | MEN1 (0.37) | HTTMEN1KMT2APRMT5WDR77 | |
| SCHEMBL9208286 | 0.73 | ADRA1B (0.41) | HTTPRMT5WDR77ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9214235 | 0.73 | ADRA1B (0.41) | HTTPRMT5WDR77ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9207178 | 0.72 | ADRA1B (0.41) | HTTMEN1KMT2APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |