SCHEMBL9215643

SCHEMBL9215643

[O]c1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.74
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 3/20 0.47
PKM P14618 1/20 0.47
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632609 0.89 ALDH1A1 (0.55) HTR6ALDH1A1POLBMAPTTSHR
SCHEMBL5051390 0.89 HTR6 (0.93) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL27515700 0.86 HTR6 (0.62) HTR6ALDH1A1TSHRPKMCYP3A4
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL30255 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL28119187 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.86 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2POLBMAPT
(Phenylsulfonyl)Benzene SCHEMBL25435825 0.83 HTR6 (0.93) HTR6ALDH1A1SMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418122-A Compound which prevents fading and discoloration FUJI PHOTO FILM CO., LTD. (JP) 1995-05-23 US disclosed